Copies of pseudocatalase are advertised worldwide. One ineffective copy of pseudocatalase cream plus calcium (P-CAT) has been advertised by Northwestern University in Chicago, Illinois, USA. Much confusion has taken place since the same name has been used from the original publication by Schallreuter et al 1995. The publications from Schallreuter et al on the subject of pseudocatalase formed the basis to support the efficacy of this product. More recently, Community Drug, Pittsburgh, USA, and McDonald's Pharmacy, Vancouver, BC, Canada, are offering the same formulation for sale via the internet. There are no published results in the peer-reviewed journals on P-CAT.
Both creams have been examined and analysed in our laboratory in vitro and in vivo on vitiligo skin. The data clearly shows that both copied pseudocatalase complexes are identical but have very little effect in the removal of H2O2. (Figure 1)
BE AWARE OF ADVERTISED PSEUDOCATALASE PRODUCTS WHERE THERE ARE NO PEER REVIEWED PUBLICATIONS IN THE INTERNATIONAL DERMATOLOGY JOURNALS THAT SUPPORT OR SUBSTANTIATE THE EFFICACY OF THESE PRODUCTS.